Abstract: Abstracts Objective：To investigate the clinical value of percussive mobilizer sputum elimination apparatus in pulmonary infection combined with respiratory failure. Methods：From July 2008 to July 2010, 58 patients with pulmonary infection combined with respiratory failure were randomly divided into two groups: 29 patients in group A (treatment goup) and 29 patients in group B (control group). A group were treated with G5 Percussive Mobilizer made in America, B group were treated with knock expectoration.The SpO2, PaO2, PaCO2, moist rales of lung, expectoration, the daily sputum volume and ICU stay were observed and compared. Results：Compared group B, the efficiency of sputum elimination and improvement of moist rales were better in group A.There were significant differences between group A and group B in SpO2 ((94.48±3.18) % versus (92.21±2.88) %), PaO2 ((70.38±6.90) mmHg versus (66.31±7.49) mmHg), PaCO2 ((40.34±3.63) mmHg versus (43.41±3.27) mmHg) ICU stay ((9.31±2.59)d versus (11.66±3.53)d) (P<0.05). Conclusion：Percussive mobilizer sputum elimination apparatus had signifeant effect in assisting expectoration in patients with pulmonary infection and respiratory failure, which could help to control the infection, improve the pulmonary function and reduce ICU days. It is worthy to be popularized.

Key words: Percussive mobilizer sputum elimination apparatus, Pulmonary infection, Respiratory failure