Abstract:

[Abstract] Objective Investigating the relationship between the incidence of Primary Acute Cerebral Infarction (PACI) and seasonal variation to employ measures to prevent PACI with climate change. Methods A retrospective analysis of patients diagnosed with PACI between2009and2013in the department of Neurology of Second hospital of Tian Jin Medi? cal University (n=1198patients) was carried out. Combined with the general clinical data, we analyzed seasonal, monthly and weekly variation among PACI incidents.Results The incidence of PACI increases over years between2009to 2013 （P<0.01）. Significant difference of incidents of PACI was observed between each season (P=0.047). Incidence of PACI peaked in winter（30.33±9.63/month）, while bottomed in spring（21.83±5.36/month）. Significant difference of incidents of PACI was also observed between each months（P=0.010）. The monthly incidence was highest in January and February （33.25±9.62/month）and lowest in March and April（20.75±4.89/month）. The seasonal variation was only found in the pa? tients who are complicated with pulmonary infection (P<0.01) regardless of the presence or absence of other risk factors, such as smoking, drinking ,hypertension, coronary heart disease, and diabetes mellitus. The weekly variation of PACI was on? ly significant in patients younger than 65years old（P=0.043）. The peak incidence among a week was Monday （17.86%）,and incidence bottomed on Friday (13.36%).Conclusion Our study revealed that the incidence of PACI increase over year be? tween 2009to2013and it shew a characteristic variation with respect to season, month and week. Based on these results, we can formulate prevention measures accordingly.

Key words: Acute Cerebral Infarction, Primary, Time Variations, Seasonal Variation, Monthly Variation, Weekly Variation