Abstract: [Abstract] Objective To discuss the effect on intra-abdominal pressure by different mechanical ventilation parameters. Methods 42 cases with mechanical ventilation suffering from chronic obstructive pulmonary diseases and respiratory failure were selected for observing the effects on intra-abdominal pressure by changing Tplat, Tis and peep. Results Compared with Tplat and Tis, the change of peep has much more effect on intra-abdominal pressure, both in SIMV and PSV. Conclusion The alteration of peep has a great influence on intra-abdominal pressure ,which increases the importance of selecting proper mechanical ventilation parameters.

Key words: ventilation, parameters, intra-abdominal pressure