Abstract: Abstract   Objective   TO study the nasal ventilatory function of severe obstructive sleep apnea hypopnea syndrome(OSAHS) patients without nasal obstruction and nasal anatomy anomalies. Methods    102 healthy controls and 77 patients with severe OSAHS without nasal obstruction and nasal anatomy anomalies were included in this study. Acoustic rhinometry was used to measure the minimum cross-sectional area(MCA),distance of the minimal cross-sectional area to the nostril(DCAN) and the nasal volume from 0 to 5cm,2 to 5cm(V5, V2-5). Rhinomanometry was used to measure unilateral nasal inspiratory resistance (IR) and expiratory resistance (ER) at 150 pa,total bilateral inspiratory resistance(TIR) and total bilateral expiratory resistance(TER) were obtained by calculation. Rhinospirometer was used to measure unilateral inspiratory capacity(IC) and expiratory capacity(EC),and the nasal partitioning ratio(NPR) can be calculated. Results     Compared to control group, IR,ER,TIR, TER, IC, EC, NRPi and NRPe were all significantly higher (P<0.05) while V5 and V2~5 were significantly lower(P<0.05) in the OSAHS group. Conclusion     Nasal ventilatory function is abnormal in the severe OSAHS patients without nasal obstruction and nasal anatomy anomalies; pharyngeal obstruction in the OSAHS could cause the change in the nasal ventilatory function.

Key words: Sleep apnea hypopnea, obstructive, sleep apnea syndromes, rhinometry, acoustic, rhinomanometry, nose, 炎症