The correlation between excessive daytime sleepiness and sleep disordered breathing in patients after stroke

doi:10.11958/20230247

Abstract

Abstract:

Objective To explore the correlation between excessive daytime sleepiness (EDS) and sleep disordered breathing after stroke. Methods A total of 148 patients with stroke were divided into the EDS group (ESS>7, n=69) and the non-EDS group (ESS≤7, n=79) according to Epworth Sleepiness Scale (ESS). The general data, blood biochemistry and polysomnography (PSG) parameters were compared between the two groups of patients. The correlation between EDS and SDB incidence rate after stroke was analyzed by spearman test. Multivariate Logistic regression analysis was applied for influencing factors of EDS after stroke. Results There were higher proportion of males, hypoventilation index (AHI), oxygen reduction index (ODI), proportion of N1 sleep period and average nighttime diastolic blood pressure in the EDS group than those of the non-EDS group (P<0.05). There was a positive correlation between the incidence rate of EDS and SDB in stroke patients (r_s=0.225, P<0.05). Multivariate Logistic regression analysis revealed that gender (OR=2.768, 95%CI: 1.133-6.765), high AHI (OR=1.048, 95%CI: 1.023-1.074) and high average nighttime diastolic blood pressure (OR=1.035, 95%CI: 1.001-1.071) were the independent risk factors for EDS after stroke. Conclusion Male, higher AHI and high average nighttime diastolic blood pressure are independent risk factors for EDS after stroke.

Key words: stroke, sleep apnea syndromes, root cause, sleepiness during the day, multichannel sleep breathing monitoring

CLC Number:

R743.33

Figures/Tables 7

References 22

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组别	n		年龄/岁	男性		缺血性卒中
EDS组	69		60.39±11.86	60（86.9）		60（86.9）
非EDS组	79		60.18±10.39	52（65.8）		71（89.9）
t或χ²			0.117	8.937^＊＊		0.308
组别		卒中病程/d			BMI/（kg/m²）
EDS组		16.00（7.00，65.00）			26.92±4.49
非EDS组		15.00（3.00，31.00）			26.15±4.04
t或Z		1.508			1.089

组别	n		年龄/岁	男性		缺血性卒中
EDS组	69		60.39±11.86	60（86.9）		60（86.9）
非EDS组	79		60.18±10.39	52（65.8）		71（89.9）
t或χ²			0.117	8.937^＊＊		0.308
组别		卒中病程/d			BMI/（kg/m²）
EDS组		16.00（7.00，65.00）			26.92±4.49
非EDS组		15.00（3.00，31.00）			26.15±4.04
t或Z		1.508			1.089

组别		n	TC/（mmol/L）		TG/（mmol/L）
EDS组		69	3.82±1.18		1.38（2.24，1.05）
非EDS组		79	3.99±1.21		1.39（1.06，2.04）
t或Z			0.854		0.375
组别	LDL-C/（mmol/L）			HDL-C/（mmol/L）
EDS组	2.19（1.68，2.70）			1.08±0.33
非EDS组	2.08（1.65，2.82）			1.10±0.27
t或Z	0.361			0.513

组别		n	TC/（mmol/L）		TG/（mmol/L）
EDS组		69	3.82±1.18		1.38（2.24，1.05）
非EDS组		79	3.99±1.21		1.39（1.06，2.04）
t或Z			0.854		0.375
组别	LDL-C/（mmol/L）			HDL-C/（mmol/L）
EDS组	2.19（1.68，2.70）			1.08±0.33
非EDS组	2.08（1.65，2.82）			1.10±0.27
t或Z	0.361			0.513

组别	n	合并高血压	高血压病程/年	夜间平均收缩压/mmHg	夜间平均舒张压/mmHg
EDS组	69	54（78.3）	8.00（0.54，10.00）	132.39±18.97	84.51±10.57
非EDS组	79	63（79.7）	6.50（3.00，10.00）	128.87±21.89	80.10±11.73
t或Z		0.049	0.344	1.037	2.406^＊