Abstract: Abstract：Objective To investigate the effectiveness of panoramic mandibular index (PMI) in detecting the bone min⁃ eral density (BMD) of mandibular bone and whole-body bone in patients with chronic end-stage renal failure. Methods A total of thirty patients with peritoneal dialysis treatment were used as experimental group and 31 healthy adults were used as control group. The panoramic jaw tomography was taken for the measurement of superior PMI (sPMI) and inferior PMI (iPMI) in two groups. The dual-energy X-ray absorptiometry (DXA) was used to detect BMD of lumbar spine bone. Data were com⁃ pared between two groups. The correlation of sPMI, iPMI and BMD of lumbar spine bone was analyzed. Results All indica⁃ tors including sPMI(0.262 2±0.026 7 vs 0.284 2±0.025 4, t=3.301) , iPMI (0.314 1±0.028 3 vs 0.334 1±0.027 5, t=2.808) and BMD of lumbar spine bone (0.832 3±0.101 0 vs 0.906 9±0.113 6，t=2.709) were significantly lower in experimental group than those in control group (P < 0.01). There was a positive correlation between sPMI and iPMI with BMD of lumbar spine bone (r=0.439 and 0.389, P < 0.05). The BMD of lumbar spine bone was significantly lower in female patients than that of male patients in control group (0.849 7±0.114 7 vs 0.968 0±0.076 3， t=3.357). The BMD of lumbar spine bone was also sig⁃ nificantly lower in female patients than that of male patients in experimental group (0.775 4±0.068 4 vs 0.882 1±0.099 9， t= 3.365). There were no significant differences in values of sPMI and iPMI between male and female patients of two groups. Conclusion The BMD of mandibular bone is lower in patients with chronic end-stage renal failure than that of the normal people. PMI index is a simple and effective method to detect the BMD of mandibular bone, which can reflect the BMD of whole body bone in patients with chronic end-stage renal disease.

Key words: chronic renal failure, bone mineral density, panoramic mandibular index, panoramic tomogram, mandibular