天津医药

天津医药 ›› 2018, Vol. 46 ›› Issue (12): 1357-1362.doi: 10.11958/20180991

• 综述 • 上一篇    下一篇

慢性肾脏病继发甲状旁腺功能亢进的手术治疗

安宏，庞毅，徐辉，孟祥朝   

  1. 1天津医科大学研究生院（邮编300070）；2天津市第三中心医院普外科
  • 收稿日期:2018-06-25 修回日期:2018-10-18 出版日期:2018-12-15 发布日期:2019-01-24
  • 通讯作者: 安宏 E-mail:ANHONG_WN@163.COM

Surgical treatment of secondary hyperparathyroidism in patients with chronic kidney disease

AN Hong,PANG Yi,XU Hui,MENG Xiang-chao   

  1. 1 Graduate School of Tianjin Medical University, Tianjin 300070, China;2 Department of General Surgery, Tianjin Third Central Hospital
  • Received:2018-06-25 Revised:2018-10-18 Published:2018-12-15 Online:2019-01-24

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摘要： 继发性甲状旁腺功能亢进（SHPT）是慢性肾脏病（CKD）的常见并发症，生理上以甲状旁腺激素过度合成和分泌、甲状旁腺细胞过度增生为特点，引起心肌、皮肤、骨骼、造血系统及脂质代谢等多系统病变，严重影响CKD患者生活质量。本文综合国内外文献对SHPT的发病机制、手术治疗、介入治疗的现状进行总结，旨在增加对慢性肾脏病继发甲状旁腺功能亢进症（CKD-SHPT）的认识，提高CKD患者生活质量，更好地完成对SHPT疾病的诊治工作。

关键词: 肾功能衰竭, 慢性, 甲状旁腺功能亢进症, 继发性, 甲状旁腺切除术, 手术治疗, 介入治疗

Abstract: Secondary hyperparathyroidism (SHPT) is a common complication of chronic kidney disease (CKD).Physiologically，it is characterized by excessive synthesis and secretion of parathyroid hormone and excessive hyperplasia of parathyroid cells，causing multiple systemic diseases such as myocardium, skin，bone，hematopoietic system and lipid metabolism，which seriously affects the quality of CKD patients. This article summarizes the pathogenesis, surgical treatment and interventional treatment of SHPT in the literature at home and abroad. It aims to increase the understanding of secondary hyperparathyroidism in chronic kidney disease and improve the quality of life of patients with CKD, and to better complete the diagnosis and treatment of SHPT diseases.

Key words: kidney failure, chronic, hyperparathyroidism, secondary, parathyroidectomy, surgical procedures,operative, interventional therapyOperative, Interventional therapy