天津医药

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天津市男性公安民警代谢综合征危险因素分析

绳建敏1,田凤石2,汤乃军3,岳 松2,于智睿4,王亚莎3   

  1. 1. 天津市公安医院内一科
    2. 天津市公安医院
    3. 天津医科大学
    4. 天津出入境检验检疫局工业品中心
  • 收稿日期:2011-05-27 修回日期:2011-08-09 出版日期:2011-11-15 发布日期:2011-11-15
  • 通讯作者: 绳建敏

Study on the Risk Factors of Metabolic Syndrome

  • Received:2011-05-27 Revised:2011-08-09 Published:2011-11-15 Online:2011-11-15

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摘要： 摘要 目的：探讨天津市不同年龄男性公安民警代谢综合征（MS）发病危险因素的异同。方法：对1 250例健康体检的男性公安民警根据临床资料分为代谢综合征（MS）组和非MS（nMS）组, 分析2组间肝功能、肾功能、血脂、心率、白细胞、血小板、纤维蛋白原和血沉的变化。以40岁作为年龄界线，将民警分为<40岁组和≥40岁组，分析2组MS发病的危险因素。结果：MS 组丙氨酸转氨酶、碱性磷酸酶、γ-谷氨酰转移酶、总蛋白、白蛋白、球蛋白、尿酸、总胆固醇、低密度脂蛋白胆固醇、心率、白细胞和纤维蛋白原水平均明显高于nMS 组，MS 组高密度脂蛋白胆固醇水平明显低于nMS组，差别均有统计学意义（P<0.05）。<40岁民警MS发病的危险因素包括血清丙氨酸转氨酶、血尿酸、血清纤维蛋白原的升高和心率的增加，其中血清纤维蛋白原OR=2.056,95%CI 1.125~3.759。≥40岁民警MS发病的危险因素包括血清总蛋白、血尿酸、γ-谷氨酰转肽酶、白细胞的升高和心率的增加。结论：高纤维蛋白原血症是40岁以下男性民警代谢综合征的高致病危险因素

关键词: 代谢综合征X, 年龄因素, 警察, 危险因素, 纤维蛋白原, Logistic模型

Abstract: Abstract Objective: To study the risk factors of metabolic syndrome by the cases of Tianjin policemen within different ages. Methods: 1250 policemen were divided into MS group and non- MS group by their clinical dates, and the changes of the levels of liver function, renal, lipid, heart rate, WBC, PLT, FIB and ESR which were analyzed. The policemen have been divided into two groups as less than 40 years old and over 40 years old group to study the difference of the risk factors of MS by the two groups. Result: MS group on alanine aminotransferase(ALT), alkaline phosphatase(ALP), γ-glutamyl transferase(gamma GT), total protein(TP), albumin(ALB), globulin(GLB)，uric acid (UA), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), heart rate (HR), WBC and FIB were significantly higher than non-MS group, however, the high-density lipoprotein cholesterol (HDL-C) levels were significantly lower than non-MS group, the difference was statistically significant (P<0.05). The risk factors of the policemen under the age of 40 are serum alanine aminotransferase, UA, FIB, and HR. while the risk factors beyond the age of 40 are serum total protein, UA, gamma GT, WBC, and HR. Conclusion: FIB is high-risk factors for MS under the age of 40.