天津医药

• 短篇论著 • 上一篇    下一篇

天津地区儿童急性呼吸道感染病毒病原检测分析

王维1,李胜英2,张桦1,林书祥2,黄敬孚1   

  1. 1. 天津市儿童医院儿科研究所
    2. 天津市儿童医院
  • 收稿日期:2011-12-21 修回日期:2012-03-19 出版日期:2012-06-15 发布日期:2012-06-15
  • 通讯作者: 王维

Epidemiological Research of Seven Kinds of the Respiratory Tract Virus Associated Acute Respiratory Tract Infections in Hospitalized Children of Tianjin

  • Received:2011-12-21 Revised:2012-03-19 Published:2012-06-15 Online:2012-06-15

PDF (PC)

2562

摘要： 摘要 目的：了解天津地区儿童急性呼吸道感染的病毒病原情况。方法：采用直接免疫荧光法，对从2010 年1 月至2011 年6 月一年半期间天津市儿童医院收治的5954 例0 ~12 岁急性呼吸道感染住院儿童鼻咽分泌物标本进行呼吸道七种病毒检测。结果：5954 例样本中有626 例检测出阳性结果，总阳性率为10.51 %。其中呼吸道合胞病毒（RSV）检出最多，为376 例（60.06 %），其余依次为副流感病毒3（PIV 3）211 例（33.71 %），腺病毒（ADV）20 例（3.19 %），流感病毒A（IFV A）6 例（0.96 %），副流感病毒1（PIV 1）5 例（0.80 %），流感病毒B（IFV B）3 例（0.48 %），副流感病毒2（PIV 2）2 例（0.32 %）和混合感染3 例（0.48 %）。RSV 在各年龄组患儿中检出率均为最高，其余几种病毒感染以2 岁以内婴幼儿多见。RSV 季节性较明显，主要集中在冬春季，PIV 3 在夏季有一个小高峰。结论：天津地区男性儿童感染呼吸道病毒的阳性率比女性患儿高。呼吸道合胞病毒、副流感病毒3 为本地区儿童急性呼吸道病毒感染主要致病原, 发病年龄主要在婴幼儿，不同季节有一定的流行规律。

关键词: 急性呼吸道感染, 病毒感染, 儿童, 病原检测分析

Abstract: Abstract Objective: To understand the epidemiologic feature of virus infection in the children with acute respiratory tract infections in Tianjin area. Methods: From January 2010 to June 2011, 5954 hospitalized children with acute respiratory tract infection were studied. Nasopharyngeal aspirates were detected for seven kinds of the respiratory tract virus by direct immunofluorescent assay. Results: Viruses were identified in 626 patients, the positive ratio was 10.51 %, the majorty of them were under 2 years old. The most prevalent virus was respiratory syncytial viruses (RSV) (376, 60.06 %)，followed by parainfluenza 3 (211, 33.71 %), adenovirus (20, 3.19 %), influenza A (6, 0.96 %)，parainfluenza 1 (5, 0.80 %), influenza B (3, 0.48 %), parainfluenza 2 (2, 0.32 %) and coinfection (3, 0.48 %). RSV was maximum for the children between 0 to 12 years old. The seasonal change of RSV and PIV 3 was obvious. RSV was most detected in spring and winter, and the peak of PIV 3 appeared in summer. Conclusion: RSV and PIV 3 was the most common viruses in children with acute respiratory tract infections in Tianjin area, especially in children under 2 years old. Both RSV and PIV 3 had their own epidemiologic feature in different seasons.

Key words: Acute respiratory tract infection, Virus, Children, Epidemiological research