• 短篇论著 • 上一篇    下一篇

非体外循环冠状动脉旁路移植术后影响桥血管中远期通畅率的危险因素

王道彧1,姜楠2,王联群3,刘建实2,李军山2,魏东2,郭志刚3   

  1. 1. 天津医科大学
    2. 天津市胸科医院心外科
    3. 天津市胸科医院
  • 收稿日期:2012-11-08 修回日期:2013-04-09 出版日期:2013-05-15 发布日期:2013-05-15
  • 通讯作者: 王道彧

The Risk Factors of Mid and Long-term Patency Rate for Grafts after Off-pump Coronary Artery bypass Grafting

  • Received:2012-11-08 Revised:2013-04-09 Published:2013-05-15 Online:2013-05-15

摘要:

【摘要】 目的  分析非体外循环冠状动脉旁路移植术(OPCABG)后桥血管的中远期通畅率及其危险因素。方法 OPCABG术后复查的患者113例。根据搭桥术后再血管化的程度分为通畅组和病变组,比较2组的性别、年龄、既往病史和血脂情况。采用多因素Logistic回归分析OPCABG术后影响桥血管中远期通畅率的危险因素。结果  2组间性别、OPCABG术后随访时间、旁路血管数量、术后再发心绞痛比较,差异有统计学意义。女性和旁路血管数量增加是影响OPCABG术后桥血管通畅的危险因素。结论 OPCABG术后的中远期通畅率与性别、旁路血管数量密切相关。 

关键词: 冠状动脉旁路移植术, 非体外循环, 手术后期间, 危险因素, Logistic模型

Abstract: Abstract  Objective To analyze the mid and long-term patency rate for grafts after off-pump coronary artery bypass grafting and the risk factors of patency rate. Methods  Seven thousand five hundred and twenty-one patients were underwent CABG in Tianjin Chest Hospital, one hundred and thirteen cases underwent OPCABG were followed up, among them, fifty-four cases were followed up by searching the coronary artery angiography and fifty-nine cases were followed up by searching dual Source CT. The patients were 70 males and 43 females with a mean age of 63.02±8.83 years at the time of surgery. Preoperative coronary angiography revealed one-vessel disease in 5 patients, two-vessel disease in 13 patients, three-vessel disease in 95 patients, and left main coronary artery disease with or without peripheral coronary artery disease in 32 patients.Eighty-six patients had high blood pressure, 42 patents had diabetes mellitus,26 patents had hyperlipidemia,36 patents had old Myocardial Infarction,14 patents had old cerebral infarction,40 patents had a smoke by now and 31 patients were older than 70 years. The mean following up period was 27.01±18.59 months and the average number of distal anastomoses per patient was 2.96±0.86. Internal thoracic arteries (ITA) were used in 75 and saphenous veins were used in 260 . Calculate the patency rate for arterial graft and the patency rate for saphenous vein grafts respectively and analyse the risk factors of mid and long-term patency rate for grafts after off-pump coronary artery bypass grafting. Results  The patency rate of all grafts after coronary artery bypass grafting was 83.0%;and 98.0% for internal thoracic arteries; the one year and five years patency rate was 98.6% and 88.5% for ITA; the patency rate was 78.1% for saphenous vein grafts, and the one year and five years patency rate was 85.9% and 61.3% for saphenous vein grafts; the patency rate with angina group was 78.9% and 92.2% for angina-free group, there were differences between the two groups(P=0.007. Conclusion   The ITA grafts have a better long-term patency than saphenous vein grafts;The follow -up period after OPCABG、the average number of distal anastomoses and the female were independent risk factors of patency rate for grafts after CABG; Graft lesion after CABG is an important factor leading to postoperative recurrent angina pectoris.

Key words: postoperative period, risk factors, Logistic Models