关键词: 甲状腺功能减退症, 心血管疾病, 冠心病, 动脉粥样硬化, 心力衰竭, 亚临床甲状腺功能减退症, 甲状腺素治疗, 综述

Abstract: Abstract: Subclinical hypothyroidism is a metabolic disease, defined by increased thyroid-stimulating hormone (TSH) and accompanied by normal thyroid hormone levels. Recent years, many domestic and foreign studies have showed that sub⁃ clinical hypothyroidism may be related with atherosclerosis and left ventricular diastolic dysfunction, which increasing the risk and mortality of cardiovascular diseases. Subclinical hypothyroidism may be associated with lipid metabolic disorders, hypertension, coagulation dysfunction, endothelial dysfunction, abnormal glucose metabolism, homocysteine, C-reactive pro⁃ tein and lipoprotein. At present, controversy persists on the subclinical hypothyroidism. The aim of this study is to review the correlation between cardiovascular diseases and subclinical hypothyroidism.

Key words: hypothyroidism, cardiovascular diseases, coronary disease, atherosclerosis, heart failure, subclinical hypothyroidism, thyroxine therapy, review