Abstract: Biliary atresia (BA) is a common cause of obstructive jaundice in the infantile period, and also a severe hepatobiliary disease leading to liver failure. At present, the research on the etiology and pathogenesis of BA is continuing. But various signs show that perinatal viral infection plays an important role in the occurrence and development of BA, which may be the exact cause of BA. Therefore, this paper mainly discussed the feasibility of preventing BA from the view of virus vaccination, in order to provide a new perspective for reducing the incidence of BA.

Key words: biliary atresia, cytomegalovirus, rotavirus, herpesvirus 4, human, reoviridae, vaccines