Abstract: Objective To compare the difference of perioperative clinical indicators between laparoscopic partial splenectomy (LPS) and laparoscopic total splenectomy (LTS) in benign splenic space-occupying lesions. Methods Fiftytwo patients were divided into the LPS group (the lesion was located at the poles of spleen, n=22) and the LTS group (the lesion was located in the middle of spleen or close to spleen, n=30) according to the location of the lesion. The intraoperative condition, postoperative recovery and the incidence of thrombocytosis were compared between the two groups. Results Compared with the LPS group, the operation time was shortened in the LTS group, and the amount of intraoperative blood loss and blood transfusion were reduced (P＜0.01). There were no significant differences in the time of exhaust, defecation and ground activity after operation between the two groups (P＞0.05). The extubation time and postoperative hospital stay were longer in the LPS group than those in the LTS group (P＜0.05), but there was no significant difference in total hospitalization expenses between the two groups (P＞0.05). There was no postoperative blood transfusion in the two groups. The incidence of thrombocytosis during hospitalization and after discharge was lower in the LPS group than that in the LTS group (P＜0.05). Conclusion For patients whose lesions are located at the edge of spleen, laparoscopic partial splenectomy is a safe and mature treatment method, which can reduce the incidence of postoperative thrombocytosis.

Key words: splenectomy, laparoscopes, thrombocytosis, partial splenectomy, total splenectomy, benign spaceoccupying lesions of the spleen