Tianjin Medical Journal ›› 2022, Vol. 50 ›› Issue (12): 1335-1339.doi: 10.11958/20220671

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Research advance on circRNA in acute ischemic stroke

ZHENG Jiqing1(), LONG Yaobin1,(), LIU Yun2   

  1. 1 Department of Rehabilitation, the Second Affiliated Hospital, Guangxi Medical University, Nanning 530007, China
    2 Department of Orthopedics, the First Affiliated Hospital of Guangxi Medical University
  • Received:2022-05-05 Revised:2022-06-06 Published:2022-12-15 Online:2022-12-30
  • Contact: LONG Yaobin E-mail:zhengjiqing@sr.gxmu.edu.cn;long232316@163.com

Abstract:

In recent years, circularRNA (circRNA) mediated endogenous competitive RNA (ceRNA) regulatory network has been proved to play a key role in pathological and physiological processes following acute ischemic stroke (AIS) injury. Moreover, circRNA is expected to be a biomarker of AIS after the wide application of molecular diagnostic tools. The summary of the above studies can broaden the vision of the pathogenesis of AIS and provide new ideas for its diagnosis and treatment.

Key words: stroke, brain ischemia, RNA, circular, biomarkers, competing endogenous RNA

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