Abstract: Abstract: Objective To investigate the relationship between body mass index (BMI), blood lipid level and cancer dectection on prostate biopsy. Methods A total of 214 patients undergoing a prostate biopsy during 2013.2—2014.8 were reviewed retrospectively. They were divided into prostate cancer and non-cancer groups by biopsy results. The differences of age, prostate-specific antigen (PSA) level, prostate volume (PV), blood lipid level and BMI between two gtoups were analyzed. Risk factors for cancer dectection on biopsy were also analyzed. Results Compared with non-cancer patients, prostate cancer patients were older, had higher PSA level and BMI, but smaller PV and lower HDL-c level (P<0.05). Logistic regression analysis showed that older, higher PSA level and BMI were risk factors for cancer dectection on biopsy, but larger PV and higher HDL-c level were protective factors (P<0.05). Conclusion Comprehensive assessment of patients’ BMI and blood lipid levels can provide important reference for prostate cancer screening at early time and establishment of prostate biopsy scheme, which also provide significant evidence for the prevention, diagnosis and treatment of prostate cancer at early stage for high risk population.

Key words: prostatic neoplasms, punctures, body mass index, cholesterol, HDL, prostate-specific antigen, prostate volume