• 论著 • Previous Articles     Next Articles

Analysis on the relationship between anemia and heart function in hospitalized patients with chronic heart failure caused by coronary heart disease

  

  • Received:2010-08-20 Revised:2010-12-01 Published:2011-04-15 Online:2011-04-15
  • Contact: Yuan-Yuan ZHAO

Abstract: Objective: To investigate the relationship between anemia and heart function in hospitalized patients with chronic heart failure caused by coronary heart disease. Methods : 1816 patients which were hospitalized between Dec 2005 and Jan 2007 in the second hospital of Tianjin medical university were analyzed. The retrospective indexes include anemia, heart function. Results: 1816 cases were enrolled and the distribution of gender has no statistical significance. Among these cases, 305(13.8%) were found to have anemia ,the proportion of which in male and female is 16.34%(151/925)and .28 % (154/891) respectively (p>0.05).The average age in anemia set is older than that of the non-anemia set (t=6.823,P<0.01).The proportion of anemia in over 60 years elders is higher than that of under 60 years elders(χ2=13.312,p<0.01) . With the progression of heart function classification, the value of hemoglobin has a lower gradually trend, the prevalence of anemia has a higher gradually trend. Between heart function classification and the value of hemoglobin take the negative relationship ( r=-0.192,p<0.05) .LVEDD of anemia set is higher than the non-anemia, IVS is lower. Anemia set has a majority proportion of LVEF(≤45%),while, LVEF in non-anemia set is mainly >45%.The proportion of E/A≤1 is more than E/A>1 in both sets and E/A≤1 is more in non-anemia set, these differences all have statistic significant. Conclusion: Coronary Chronic Heart Failure usually accompanies with anemia, and then anemia can make the degree of CHF aggravate, increase the hospital mortality and form vicious circle. Therefore while in the treatment of heart failure, we should actively correct anemia, this can significantly improve the prognosis of patients with Chronic Heart Failure.

Key words: Coronary Heart Disease, Chronic Heart Failure, Anemia, Left Ventricular Ejection Fraction, Heart Function Classification