Abstract: Abstract: Objective To investigate the relationship between the fragmented QRS (fQRS) and the degree of coronary
artery lesion and left ventricular function in patients with non-ST elevation acute myocardial infarction (NSTEAMI).
Methods Data of 183 patients with NSTEAMI who underwent coronary angiography in the department of cardiology of our
hospital from January 2018 to October 2019 were retrospectively analyzed. According to the presence of fQRS (two or more
adjacent leads) on the resting ECG, patients were divided into fQRS group (n=84) and nfQRS group (n=99). The clinical
characteristics, coronary angiography data and echocardiography were analyzed between the two groups. Results The blood
biochemical indexes such as cTnI, CK, CK-MB, LDH, TC, TG, LDL-C, Scr and hs-CRP were significantly increased in
fQRS group compared to those of nfQRS group (P＜0.05). Gensini score and NT-proBNP value were significantly higher,
LVEF was significantly lower, in fQRS group than those in nfQRS group (P＜0.01). Logistic regression analysis showed that
the higher cTnI, CK-MB and Gensini score, and the lower LVEF were risk factors for fQRS in NSTEAMI patients. The fQRS
group was then divided into two subgroups. The Gensini score of the lead number > 3 and the proportion of coronary artery
lesion＞3 were significantly higher than those with the lead number≤3 group. Conclusion For NSTEAMI patients with
fQRS on the ECG, especially those with more leads of fQRS, the coronary artery lesion is more serious, the left ventricular
function is worse and myocardial ischemia is more severe.

Key words: non-ST elevation acute myocardial infarction, fragmented QRS, coronary angiography, Gensini score, left ventricular ejection fraction