Abstract: Objective： To analysis the relationship between the cardiac functional grading and the level of thyroid hormone, B-type natriuretic peptide(BNP),Left ventricular ejection fraction(LVEF).Methods:The 150 patients have been divided into 4 groups,the chronic congestive heart failure(CHF) group and the control group.All the patients have been measured the levels of free triiodothyronine (FT3),total triiodothyronine(TT3),free thyroxine (FT4), total thyroxine（TT4）, thyroid-stimulating hormone(TSH) and BNP in the plasma by the radioimmunoassay and the immunofluorescence method.Meanwhile to monitor the LVEF by Echocardiography.Result: The level of the FT3、TT3 and LVEF are lower in the CHF group than in the control group with significant difference,while the BNP level are higher in the CHF group with significant difference; According to the cardiac functional grading,there are significant difference in the FT3、TT3,BNP and LVEF in patients. Conclusion: The level of the thyroid hormones,LVEF and BNP can be the indicators to evaluate the extent of CHF.

Key words: congestive heart failure, thyroid hormone, brain natriuretic peptide