Tianjin Med J ›› 2015, Vol. 43 ›› Issue (6): 694-697.doi: 10.11958/j.issn.0253-9896.2015.06.031

Previous Articles     Next Articles

Research progress of transforming astrocytes into neurons

KANG Wenbo, ZHANG Sai, LIANG Haiqian   

  1. Department of Brain of Affiliated Hospital of Logistics University of Chinese people′s Armed Police Forces,
    The Key Laboratory of Tianjin Neurotrauma Repair

  • Received:2014-10-29 Revised:2015-01-30 Published:2015-06-15 Online:2015-06-10

Abstract: In recent years, the rapid development of stem cell transforming technology and regeneration pose great research value. With maturation of transformation induction, other cell lineages were shown to be able to transform into neurons. In addition, astrocytes are widely distributed in the gray and white matter of the central nervous system, whose excessive proliferation contribute to glial fibrillary scar formation, which is the key obstacle in recovery of neurological function.
Therefore, the study of transforming astrocytes into neurons draw attention from many scientists. Astrocytes transformation not only prevent the formation of glial scar, but also generate new neurons. This article summarized relevant studies that report function of astrocytes and its transformation into neurons.


Key words: cell tranformation, neurons, astrocytes