Tianjin Medical Journal ›› 2018, Vol. 46 ›› Issue (6): 654-656.doi: 10.11958/20171327

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Case report and literature review of neonatal hemolysis induced by anti-E and anti-Ec combined with anti-Fyb

SHI Wu-juan, MU Yu, SONG Li, ZHANG Fang, MA Qing-rong, WANG Dan   

  1. Department of New Pediatric, Tianjin Children’s Hospital, Tianjin 300134, China
  • Received:2017-11-23 Revised:2018-03-12 Published:2018-06-15 Online:2018-07-05
  • Contact: wu-juan shi E-mail:13132163129@163.com

Abstract: Hemolytic diseases of newborn (HDN) can cause miscarriage, premature birth, fetal edema, fetal intrauterine anemia and even fetal death in early pregnancy. Neonatus with HDN can have jaundice,anemia,hepatosplenomegaly, edema and nuclear jaundice sequelae. This article reviewed the diagnosis and treatment of two patients with HDN caused by anti -E and anti-Ec combined with anti-Fyb, and reviewed the relevant literature on the epidemilogy, the diagnosis and treatment of HDN in order to improve the understanding of the disease.

Key words: anemia, hemolytic, isoimmune, Rh-Hr blood-group system, Duffy blood-group system, intensive care, neonatal