Abstract: Objective To analyze the clinical features, treatment and prognosis of intraocular metastatic tumors.Methods Sixteen patients were retrospectively analyzed to study the clinical manifestations, imaging features,treatment and prognosis of intraocular metastatic tumors. Results The ocular symptom was the first symptom in all cases. Fundus examination showed that 10 cases were grayish yellow, 3 cases were dark red, and 3 cases showed obvious retinal detachment and exudation, which covered the presence of masses. Neovascular glaucoma was found in 5 cases. Ultrasound showed that all the cases were solid lesions, and 11 cases with local retinal detachment. Ultrasound color doppler showed abundant blood flow in 6 cases, small point blood flow signal in 9 cases, and no clear blood flow signal in 1 case. Orbital CT showed definite mass in 10 cases, and local ball wall thickening in 6 cases. Eleven cases underwent orbital MRI examination, T1WI and T2WI showed moderate signal of lesion. After 3 months to 2 years of follow-up, patients were found systemic lesions,including 6 cases of lung cancer, 6 cases of digestive system tumors, 3 cases of breast cancer, and 1 case of endometrial cancer. Nine cases died of systemic disease, and 7 cases followed-up within 6 months. The general condition of the 7 cases was poor, and 3 cases showed obvious cachexia. Conclusion Intraocular metastatic tumors are solid lesions. Comprehensive ocular examination, combined with detailed medical history, and systemic examinations should be performed to detect systemic lesions in time to prevent the omission of systemic lesions.

Key words: eye neoplasms, neoplasm metastasis, choroid neoplasms