Research progress on the role and mechanism of 5-hydroxytryptamine in gastrointestinal diseases

doi:10.11958/20231309

Abstract

Abstract:

5-hydroxytryptamine (5-HT) is an important neurotransmitter in brain-gut axis pathway, and its secretion is closely related to intestinal flora, intestinal immunity and intestinal motility. Abnormal metabolic pathway of 5-HT is involved in the occurrence and development of gastrointestinal diseases, such as irritable bowel syndrome, inflammatory bowel disease, chronic constipation and functional dyspepsia. This article reviews the mechanism of 5-HT in different gastrointestinal diseases in order to explore new ideas for clinical treatment.

Key words: serotonin, 5-hydroxytryptamine, gastrointestinal diseases, intestinal flora, intestinal motility, intestinal immunity

CLC Number:

R574

References 46

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