Abstract: This study aimed to investigate the sleep disorders characteristic in frontal lobe epilepsy（frontal lobe epilepsy，FLE）through polysomnography and subjective questionnaires. Methods 18 FLE patients and 15 healthy subjects were recruited to our study. Every subject were evaluated by whole-night polysomnography and subjective questionnaires. Results Compared with controls, the FLE demonstrated an obviously increase in total time in bed[(503.22±62.33)min], wake after sleep onset[（54.11±18.97）min], number of sleep stage shifts in total sleep time[（161.17±56.83）], the number of sleep stage shifts per an hour[（22.6±6.25）], the number of NREM1 stage shifts[(42.56±15.26)] and NREM2 stage shifts[(57.28±26.57)], number of wake stage[(48.76±10.62)]. Meanwhile, FLE showed higher scores in BDI-II [(9.33±5.01)]and Fatigue scale-14[(5.72±3.36)分] compared with controls. Conclusion The sleep disorders and sleep disruption can be found in FLE, furthermore, the sleep disorders in FLE is related with depression and seizures frequency.

Key words: frontal lobe epilepsy, sleep disorders, fatigue, depression