Abstract: ST-segment elevation myocardial infarction (STEMI) is the most serious type of coronary heart disease,accounting for 25% to 40% of acute myocardial infarction (AMI). The key to treat STEMI is to restore myocardial perfusion in the infarct area, to rescue the ischemic myocardium, and to reduce the size of infarction. About 41% to 67% of patients with STEMI have multiple vascular disease (MVD). Compared with single vessel disease, the clinical outcome of MVD is worse. In these patients, it still remains a controversial topic in emergency interventions for STEMI patients, the infarct-related artery only revascularization or multi-vessel revascularization, and the timing of revascularization. The clinical studies of revascularization strategy for MVD in STEMI patients have been ongoing, and the results have also led to the continuous updating of guidelines and treatment strategies.

Key words: myocardial infarction, acute ST-segment elevation myocardial infarction, multiple vascular disease;revascularization, infarction related artery