Tianjin Medical Journal ›› 2018, Vol. 46 ›› Issue (10): 1135-1139.doi: 10.11958/20180698

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The role of heart-type fatty acid-binding protein in cardiovascular diseases

WANG Cui-hua1, LIU Yan-gong2, ZHENG Ming-qi1△   

  1. 1 Heart Center, the First Hospital of Hebei Medical University, Shijiazhuang 050031, China; 2 Department of Pathophysiology, Oita University School of Medicine, Japan △Corresponding Author E-mail: mzheng2020@163.com
  • Received:2018-05-02 Revised:2018-07-02 Published:2018-10-15 Online:2018-11-09
  • Contact: ZHENG Mingqi E-mail:mzheng2020@163.com

Abstract: Abstract: Heart-type fatty acid-binding protein (H-FABP) is a small molecular protein, which is mainly expressed in heart and plays a key role in mitochondrial β oxidation through partitioning of long-chain fatty acids toward the mitochondria. Nowadays, H-FABP is clinically used for the early diagnosis of persistent myocardial injury and acute myocardial infarction (AMI). More and more studies have showed that H-FABP is closely related to the diagnosis and prognosis of acute coronary syndrome, heart failure and arrhythmia.

Key words: cardiovascular diseases, arrhythmias, cardiac, heart failure, diagnosis, prognosis, heart-type fatty acidbinding protein, acute myocardial infarction