Abstract: Abstract：Immune thrombocytopenia (ITP), one of the most common bleeding disorders, is characterized by clinical manifestations of skin mucosa and internal bleeding and by decreased platelet count due to auto-antibody mediating the platelets destruction and insufficient platelet production. The exact etiology of ITP is still unclear so far. To fully understand the pathogenesis of ITP not only has important theoretical significance but also may provide a new strategy for the treatment of the disease. MicroRNA (miRNA) is a class of small non-coding RNAs with a length of 19-22 nucleotides. It is involved in the occurrence and development of many diseases by regulating its target genes. At present, there are more and more studies on the role of microRNAs in the pathogenesis of ITP. In this review, the progress of miRNA in the pathogenesis of ITP in recent years was summarized

Key words: thrombocytopenia, MicroRNAs, immune thrombocytopenia, review