Tianjin Medical Journal ›› 2019, Vol. 47 ›› Issue (6): 667-672.doi: 10.11958/20181936

Previous Articles    

Gut microbiota and diabetes

ZHANG Jie1 , XU Yan-cheng2△, WU Yu-wen2   

  1. 1 Department of Endocrinology, the First Hospital of Huhhot, Huhhot 010030, China; 2 Department of Endocrinology, Zhongnan Hospital of Wuhan University
  • Received:2018-12-04 Revised:2019-01-16 Published:2019-06-15 Online:2019-06-15

Abstract: Abstract: In recent years, the relationship between gut microbiota and diabetes has become a research hotspot. With the in-depth study of gut microbiota, the role of gut microbiota, as an environmental factor in regulating the development of immune and metabolic diseases, has been gradually recognized. At present, a large number of studies at home and abroad have focused on the pathogenesis of gut microbiota affecting obesity and diabetes. Some studies have also found that the gut microbiota can obtain energy from food components that are difficult to digest, affecting the energy balance and metabolism of human body. The genome sequencing method is used to reveal the composition and abundance of intestinal flora in different types of diabetes patients, and which can be verified in animals to clarify the bacterial functions associated with diabetes. The genetic information carried by the gut microbiota may be a new breakthrough in the future treatment of diabetes. There are many studies on gut microbiota in type 2 diabetes mellitus (T2DM) and type 1 diabetes mellitus (T1DM), but there have been few reports on the gut microbiota of gestational diabetes in the past. Therefore, in this paper, the characteristics of gut microbiota in different types of diabetes and the mechanism of gut microbiota involved in the occurrence of diabetes were reviewed.

Key words: gut microbiota, diabetes, review