Abstract: Abstract: Objective To evaluate the correlation between central venous oxygen saturation (ScvO2) and postpartum hemorrhage (PPH) after cesarean section and its diagnostic value for PPH. Methods A total of 30 patients underwent elective cesarean section in department of obstetrics of the First Affiliated Hospital of the University of South China from January 1, 2017 to December 31, 2017 were prospectively included. Values of hematocrit (HCT), hemoglobin (Hb), ScvO2 and hemorrhage volume were recorded before and after hemorrhage. Hematocrit differences (ΔHCT), hemoglobin differences (ΔHb), central venous oxygen saturation differences (ΔScvO2) were calculated before and after hemorrhage. The correlation between the ΔHCT, ΔHb, ΔScvO2 and hemorrhage volume was studied. The diagnostic value of ΔScvO2 to PPH was analyzed by receiver operating characteristic (ROC) curve. Results There was no significant difference in Hb and HCT in patients before and after hemorrhage (P＞0.05). The value of ScvO2 was significantly lower after hemorrhage than that before hemorrhage (P＜0.05). There was no correlation between ΔHb, ΔHCT and hemorrhage volume (P＞0.05). ScvO2 was negatively correlated with hemorrhage volume (r=-0.817, P＜0.001). The area under curve (AUC) of ΔScvO2 was 0.824 (95% CI: 0.657-0.991, P = 0.003). The diagnostic sensitivity and specificity for PPH were 66.7% and 99.4% when ΔScvO2 was -6.90. Conclusion ScvO2 is negatively correlated with PPH hemorrhage volume and can be used as a sensitive index in the diagnosis of PPH.

Key words: postpartum hemorrhage, diagnosis;, ROC curve, sensitivity and specificity, central venous oxygen saturation