Tianjin Medical Journal

Tianjin Medical Journal ›› 2019, Vol. 47 ›› Issue (12): 1258-1262.doi: 10.11958/20190015

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Comparison convex probe real-time elastography, acoustic radiation force impulse imaging and transient elastography in the diagnosis of chronic hepatitis B-related liver fibrosis

MENG Yan-na1，ZHANG Juan-juan1，CHEN Ying-hong1，LI Ying1，YU Yan-yan1，LI Zhi-yan2△   

  1. 1 Department of Ultrasound, Huaihe Hospital of Henan University, Kaifeng 475000, China; 2 Department of Ultrasound, the 302nd Hospital of PLA
  • Received:2019-01-04 Revised:2019-02-21 Published:2019-12-15 Online:2019-12-15
  • Contact: Meng YanNa E-mail:shuaiwei0909@163.com
  • Supported by:
     

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Abstract:

Objective To compare the diagnostic efficacy of convex probe real-time elastography (C-RTE), acoustic
radiation force impulse imaging (ARFI) and transient elastography (TE) in evaluating liver fibrosis. Methods One hundred
and sixty-seven patients with chronic hepatitis B (CHB) were included in this study. All patients were assessed by C-RTE,
ARFI,TE and liver biopsy respectively. The pathological results were used as the gold standard. The correlation coefficient
between C-RTE, ARFI, TE and pathological fibrosis stage was analyzed
. The areas under receiver operating characteristic
curve (AUROC) between the three methods were compared.
Results Except for C-RTE and ARFI in the diagnosis of S
0/
S1, S3/ S4, TE in the diagnosis of S0/ S1, S0/ S2, there were significant differences between other groups
.
The correlation
coefficients between C-RTE, ARFI, TE and liver fibrosis were 0.72, 0.65 and 0.68, respectively (
P＜0.001).
The areas under
the curves (AUC) of C-RTE, ARFI and TE for diagnosing S≥1, S≥2, S≥3 and S=4 were 0.812, 0.917, 0.848 and 0.785;
0.824, 0.818, 0.858 and 0.822; 0.858, 0.833, 0.876 and 0.884, respectively. The optimal cut–off values were 1.3, 1.74, 2
and 2.64; 5.3 kPa, 7.2 kPa, 8.9 kPa and 19.4 kPa; 1.29 m/s, 1.71 m/s, 1.89
m/s and
2
.02
m/s
,
respectively
. The diagnostic
efficiency of C-RTE was better than that of ARFI and TE, when S≥2, (
Z
=2
.56,2.84,
P
＜0
.01
).
Conclusion
C-RTE has
higher diagnostic efficiency for liver fibrosis and is worthy of clinical promotion
.

Key words: diagnosis, differential, elasticity imaging techniques, liver cirrhosis, hepatitis B, chronic, biopsy, needle

CLC Number: