Tianjin Medical Journal

Tianjin Medical Journal ›› 2020, Vol. 48 ›› Issue (9): 903-907.doi: 10.11958/20193232

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The application of next generation sequencing in the diagnosis and treatment of colorectal cancer#br#

CHEN Ru-ping1, 2, LIU Rui2△   

  1. 1 Graduate School of Tianjin Medical University, Tianjin 300070, China;
     2 Department of Clinical Laboratory, Tianjin Union Medical Center
  • Received:2019-10-24 Revised:2020-06-23 Published:2020-09-15 Online:2020-09-22

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Abstract: Abstract: The potential application value of next generation sequencing (NGS) technology in the clinical diagnosis and treatment of colorectal cancer (CRC) has become a research hotspot. NGS can be used not only to detect gene mutations in the early CRC screening, but also to guide the selection of targeted drugs, the predicting of the efficacy and the evaluation of the prognosis. This paper reviews the applications of NGS technology in clinical diagnosis and treatment of CRC in recent years.

Key words: colorectal neoplasms, genetic testing, molecular targeted therapy, prognosis, next generation sequencing

CLC Number: