Research progress on etiology and clinical characteristics of ICM-induced hypothyroidism

doi:10.11958/20220392

Abstract

Abstract:

Iodinated contrast media (ICM) administration may induce hypothyroidism (IIHypo). Recent studies have found that ICM can specifically inhibit thyroid iodide uptake by iodide independently of free iodide through a mechanism different from the conventional Wolff-Chaikoff effect. At present, issues regarding the incidence of IIHypo, related risk factors and indications for monitoring ICM-induced events have not been fully determined. Recognizing of potential risk factors for IIHypo and timely assessment of iodine-induced events within the time window of iodine exposure have important clinical significance for optimizing the diagnosis and management procedures of ICM-induced thyroid dysfunction.

Key words: hypothyroidism, iodinated contrast media, Wolff-Chaikoff effect, risk factors

CLC Number:

R541.4

Figures/Tables 1

References 35

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