Therapeutic effect of salvia miltiorrhiza polyphenolic acid on immune infertility rats and its effect on hypothalamic-pituitary-ovarian axis

doi:10.11958/20220990

Abstract

CLC Number:

R711.6，R593

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References 20

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组别	n	GnRH（μg/L）	FSH（IU/L）	LH（IU/L）	E2（ng/L）
正常对照组	10	88.20±15.23	3.73±0.59	6.77±1.24	56.18±10.35
模型组	9	45.72±7.54^a	1.22±0.23^a	3.05±0.56^a	25.24±4.71^a
强的松组	10	70.26±12.71^ab	2.33±0.38^ab	5.14±0.93^ab	42.39±8.04^ab
丹参多酚酸低剂量组	9	42.65±7.37^ac	1.17±0.22^ac	2.78±0.55^ac	24.67±4.51^ac
丹参多酚酸中剂量组	10	54.33±9.15^abcd	1.67±0.28^abcd	4.14±0.78^abcd	34.92±6.13^abcd
丹参多酚酸高剂量组	10	67.83±11.59^abde	2.25±0.37^abde	5.21±0.96^abde	45.80±8.29^abde
F		25.325^＊＊	61.336^＊＊	26.479^＊＊	27.293^＊＊

组别	n	GnRH（μg/L）	FSH（IU/L）	LH（IU/L）	E2（ng/L）
正常对照组	10	88.20±15.23	3.73±0.59	6.77±1.24	56.18±10.35
模型组	9	45.72±7.54^a	1.22±0.23^a	3.05±0.56^a	25.24±4.71^a
强的松组	10	70.26±12.71^ab	2.33±0.38^ab	5.14±0.93^ab	42.39±8.04^ab
丹参多酚酸低剂量组	9	42.65±7.37^ac	1.17±0.22^ac	2.78±0.55^ac	24.67±4.51^ac
丹参多酚酸中剂量组	10	54.33±9.15^abcd	1.67±0.28^abcd	4.14±0.78^abcd	34.92±6.13^abcd
丹参多酚酸高剂量组	10	67.83±11.59^abde	2.25±0.37^abde	5.21±0.96^abde	45.80±8.29^abde
F		25.325^＊＊	61.336^＊＊	26.479^＊＊	27.293^＊＊

组别	n	FSHR	LHR	ERα
正常对照组	10	1.38±0.24	1.77±0.30	2.52±0.45
模型组	9	0.29±0.05^a	0.54±0.09^a	0.49±0.08^a
强的松组	10	1.10±0.21^ab	1.32±0.23^ab	1.79±0.34^ab
丹参多酚酸低剂量组	9	0.33±0.06^ac	0.59±0.11^ac	0.52±0.09^ac
丹参多酚酸中剂量组	10	0.78±0.15^abcd	0.96±0.18^abcd	1.07±0.20^abcd
丹参多酚酸高剂量组	10	1.15±0.22^abde	1.35±0.24^abde	1.84±0.33^abde
F		62.661^＊＊	51.615^＊＊	67.607^＊＊

组别	n	FSHR	LHR	ERα
正常对照组	10	1.38±0.24	1.77±0.30	2.52±0.45
模型组	9	0.29±0.05^a	0.54±0.09^a	0.49±0.08^a
强的松组	10	1.10±0.21^ab	1.32±0.23^ab	1.79±0.34^ab
丹参多酚酸低剂量组	9	0.33±0.06^ac	0.59±0.11^ac	0.52±0.09^ac
丹参多酚酸中剂量组	10	0.78±0.15^abcd	0.96±0.18^abcd	1.07±0.20^abcd
丹参多酚酸高剂量组	10	1.15±0.22^abde	1.35±0.24^abde	1.84±0.33^abde
F		62.661^＊＊	51.615^＊＊	67.607^＊＊

组别	n	FSHR	LHR	ERα
正常对照组	10	0.75±0.13	0.87±0.16	1.12±0.21
模型组	9	0.14±0.02^a	0.26±0.05^a	0.31±0.05^a
强的松组	10	0.49±0.08^ab	0.58±0.10^ab	0.78±0.14^ab
丹参多酚酸低剂量组	9	0.16±0.03^ac	0.24±0.04^ac	0.35±0.06^ac
丹参多酚酸中剂量组	10	0.33±0.06^abcd	0.41±0.07^abcd	0.60±0.11^abcd
丹参多酚酸高剂量组	10	0.52±0.09^abde	0.55±0.09^abde	0.83±0.15^abde
F		71.035^＊＊	55.213^＊＊	48.445^＊＊

Therapeutic effect of salvia miltiorrhiza polyphenolic acid on immune infertility rats and its effect on hypothalamic-pituitary-ovarian axis

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