Abstract: Abstract :Objective To evaluate the accuracy of aldosterone to rein ratio(ARR) in diagnosing primary aldosteronism(PA). Methods The aldosterone to rein ratio was determinned in 279 patients with primary aldosteronism and 70 patients with primary hypertension(PH),the patients were divided into 11 groups according to the range of 10. The numbers of PA and PH with diffent stage of ARR were determined,and the sensitivity,specificity,Youden index of ARR in diagnosing PA were caculated.The ROC curve was drawed.　Results The value of ARR in 30～、40～、50～, the sensitivity,specificity,Youden index of ARR in diagnosing PA were 83.2%、82.9%、0.661,77.8%、88.6%、0.664 and 74.2%、92.9%、0.671,respectively. Conclusion The sensitivity,specificity,Youden index of ARR in diagnosing PA are pretty high when ARR in 30～60.

Key words: primary aldosteronism, aldosterone to renin ratio, sensitivity, specificity