Tianjin Medical Journal

Tianjin Medical Journal ›› 2021, Vol. 49 ›› Issue (8): 870-874.doi: 10.11958/20210766

• Applied Essay • Previous Articles     Next Articles

The effect of pre-test probability combined with radionuclide myocardial perfusion imaging on the diagnosis of coronary heart disease in different genders

SONG Zhi-yong1, JIANG Chao2, LUO Dong-lei3△,YAO Yan-ying3, ZHANG Lei1, LIU Lei3, HOU Yun-sheng1   

  1. 1 Department of Emergency, 980 Hospital of PLA Joint Logistics Support Forces, Shijiazhuang 050000, China; 2 Chengde Medical University; 3 Department of Cardiology, Chengde Central Hospital, Second Clinical College of Chengde Medical University △Corresponding Author E-mail: luoyutian999@126.com
  • Received:2021-03-31 Revised:2021-04-19 Published:2021-08-15 Online:2021-08-19

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Abstract: Objective To analyze the value of pre-test probability (PTP) combined with radionuclide myocardial perfusion imaging (MPI) in the differential diagnosis of coronary heart disease (CHD) in different genders. Methods A total of 270 patients with suspected CHD received by our hospital from July 2019 to December 2020 were prospectively selected as the research subjects. All patients received PTP and MPI, and the risk of CHD was preliminary assessed. The coronary angiography (CAG) was also performed. Based on the results of CAG, the diagnostic value of PTP combined with MPI was analyzed in patients with CHD and CHD patients of different genders. Results Among 270 suspected CHD patients, 188 cases (69.63%) were CHD, including 110 male patients and 78 female patients after CAG examination. Based on the examination results of CAG, 176 patients with CHD were detected by PTP combined with MPI, and the total coincidence rate was 93.62%, of which there were 107 male patients and 69 female patients. The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of female patients diagnosed by PTP combined with MPI were 88.46%, 88.89%, 88.60%, 94.52% and 78.05%, respectively, which showed the ideal consistency with the results of CAG (Kappa= 0.746). The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of male patients diagnosed by the PTP combined with MPI were 97.27%, 95.65%, 96.79%, 98.17% and 93.62% respectively, which were in good agreement with the results of CAG (Kappa=0.923). The sensitivity, accuracy and negative predictive value of PTP combined with MPI in the diagnosis of CHD were significantly higher in male patients than those of female patients (P＜ 0.05). Conclusion PTP combined with MPI examination has a higher diagnostic value for CHD, and the sensitivity and accuracy are higher in male patients with CHD than those of female patients.

Key words: coronary disease, myocardial perfusion imaging, sex factors, sensitivity and specificity, pre-test probability

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