Abstract: Abstract Objective: To examine correlation factors for vascular dementia （VD）after cerebral infarction. Methods: A total of 392 patients were enrolled, and related clinical data and laboratory examinations were collected. Risk factors for VD were determined by using multiple logistic regression analysis. Results: Eighty-four participants (21.4%) were diagnosed as VD. Univariate analysis found that VD was associated with number of lesions, location of lesions, leukoaraiosis and cerebral atrophy. Multivariate logistic regression suggested that left hemisphere or bilateral lesions (OR=8.958) 、number of lesions(OR=1.375) and cerebral atrophy(OR=2.297) were independent risk factors of VD. VD was unrelated to age, education, or vascular factors (hypertension, diabetes, coronary heart disease, or hyperlipidemia ). Conclusions: Vascular dementia is frequent after ischemic stroke. Cerebral small vessel disease (SVD) is a major cause of VD. Better knowledge of the risk factors for VD should be emphasized to reduce the attacks of vascular dementia.

Key words: vascular dementia, risk factors, cerebral infarction