Abstract: Objective：To discuss the possible causes of recurrent ovarian epithelial cancer in Ⅲ stage Methods：A total of 85 ovarian epithelial cancer patients in Ⅲ stage were allocated to recurrent group （31patients） and non-recurrent group （54 patients）. CA-7000 automated coagulation analyzer was used to examine the level of plasma fibrinogen （FIB）, plasma prothrombin time（PT）, thrombin time（TT）, activated partial thromboplastin time（APTT）, PLT was measured by Sysmex KX-21; CA125 was measured by electro-chemiluminescence, volume and quality of ascites, FIGO substages, histological type and grades, size of residual tumor during operation, pelvic or abdominal lymph node resectable or not and CA125 level of plasma 2 months after operation. Univariate analysis and multivariate logistic regression analysis were used to differentiate between recurrence and non-recurrence patients. Result：In univariate analysis, there was significant difference in the level of PT and TT, the rate of positive peritoneal cytology, the rate of ≥2cm residual tumor, the rate of lymph node unresected and the rate of CA125 not declined to normal 2 months later after operation between patients of recurrence and non-recurrence（P<0.05）. Multivariate analysis showed that ≥2cm residual tumor， the rate of positive peritoneal cytology, the rate of lymph node unresected and CA125 not declined to normal 2 months later after operation were important dangerous factors for recurrence of patients in Ⅲ stage（P<0.05）. conclusion：In patients of ovarian epithelial cancer in Ⅲ stage， residual tumor, peritoneal cytology, lymph node resected or not and CA125 level 2 months after operation were important prognostic factors of recurrence.

Key words: ovarian epithelial cancer, CA125, recurrence, lymph node resection, Logistic models