Abstract: 【Abstract】Objective To evaluate feasibility of bronchofibroscope alveolar wash therapy during intravenous anesthesia with laryngeal mask insertion. Methods 60 patients scheduled alveolar wash therapy, aged 45~59, were randomly divided into group LA(n=20), group GA-M(n=20) and group GA-L(n=20). After 2% lidocaine inhalation, patients in group GA-L and group GA-M anaesthetize by intravenous sedatives。Group GA-L inserted laryngeal mask，and group GA-M administrated face mask. Record completion time and awakening time. Observe the responsive symptom such as body movement, bucking, breathholding and dyspnea. Ask patients about the situations of painful memories. Record interrupt operation times and the lavage fluid recovery rate. Results Compared with group LA, there is lower body movement and bucking rate in group GA-L and group GA-M（P<0.05）. Compared with group GA-M, the incidence of dyspnea is lower in group GA-L（P<0.05）. Compared with group LA, the incidence of painful memories is lower in group GA-L and group GA-M（P<0.05）. Compared with group LA, interrupt operation times is significantly lower in group GA-L and group GA-M（P<0.05）,and that in group GA-L is lower than in group GA-M（P<0.05）. Compared with group LA, the lavage fluid recovery rate is higher in group GA-L and group GA-M（P<0.05）. Conclusion Bronchofibroscope alveolar wash therapy during intravenous anesthesia with laryngeal mask insertion can provide effective therapeutic efficacy ,increase safety, reduce the responsive symptom and decrease incidence of painful memories.

Key words: bronchoscope, alveolar wash, Laryngeal masks, general anaesthesia, intravenous