Abstract: Abstract: Objective: To investigate the relationship between donor glomerular filtration rate and post-transplant graft function in living kidney transplantation Methods: A retrospective analysis of 125 cases of living donor kidney transplantation (without acute rejection or delayed graft function, follow-up for 2 years) ,donor estimated glomerular filtration rate ,recipient estimated glomerular filtration rate at 1week and1 ,2 years post transplantation. Using the correlation method to analyze the relationship between them. Using multiple linear regression analysis of he relationship between donor weight, donor age, donor GFR, recipient age, recipient weight and recipient GFR at 1 year post transplantation . Results: The GFR of recipients at 1week,1 ,2 years post transplantation were significant correlated with the donor GFR(r=0.217 p=0.015,p = 0.039 and p = 0.003 respectively ). According to multiple stepwise regression analysis, donor GFR and recipient body weight were predictors of grft function at 1 year post transplantation, the linear regression equation : recipient GFR at 1 year post transplantation=79.9－0.49×recipient body weight＋0.24×donor GFR。 Conclusion: The donor GFR was the important characteristic for predicting the grft function in living kidney transplantation

Key words: kidney transplantation, donor, graft function, GFR