Abstract: Usefulness of Tei Index Derived from Tissue Doppler Imaging for Assessment of Right Ventricular Function in Patients with Pulmonary Arterial Hypertension Zhou Guiming, Zhao Lihui, Huang Canliang, Jia Lili, Chen Jingwan，Wanzheng Abstract Objective: To discuss the value of echocardiographic Tei index derived from Tissue Doppler Imaging(TDI) in evaluating right ventricular(RV) function in patients with pulmonary arterial hypertension(PAH).Methods: Sixty-three patients with pulmonary arterial hypertension were enrolled in this study. The patients were divided into three groups, mild group(PASP30～49 mmHg):included 21patients; moderate group(PASP50～69 mmHg): included 21 patients; severe group (PASP ≥70mmHg).Thirty-five normal individuals were enrolled as the control group.The Doppler sample volumes were placed at the interventricular septum(IVS) and RV free wall(RVFW) sites of tricuspid annular from the apical four-chamber view. RT,ICT,ET and RV Tei index were measured from IVS and RVFW by the TDI echocardiography. Results: (1) RV Tei index were of significant statistical difference among the four groups. (2) IRT were significantly higher in mild, moderate and severe groups compared with control group.And they were higher in severe group than in mild group, while there were no significant statistical difference between severe group and moderate group.ICT were significantly higher in severe group than in mild group, moderate group and control group.ET were significantly lower in severe group than control group，while there were no significant statistical difference between mild group, moderate group and severe g=-=++9roup . (3)RV Tei index derived from RVFW were of significant statistical fifference among the four groups,while there were no significant statistical difference between mild and moderate group when it mentioned to RV Tei derived from IVS.Conclusion:Tei index derived from TDI can reflect right ventricular function in patients with pulmonary arterial hypertension sensitively and exactly.

Key words: Echocardiography, pulmonary arterial hypertension, tissue doppler imaging, right ventricular function, Tei index