天津医药 ›› 2019, Vol. 47 ›› Issue (8): 880-884.doi: 10.11958/20190768

• 综述 • 上一篇    下一篇

前列腺癌诊断标志物检测研究进展

李丽,宋茜,刘冉录△   

  1. 天津医科大学第二医院泌尿外科,天津市泌尿外科研究所(邮编300211)
  • 收稿日期:2019-03-15 修回日期:2019-04-18 出版日期:2019-08-15 发布日期:2019-08-16
  • 通讯作者: 刘冉录 E-mail:liuranlu1976@126.com
  • 作者简介:李丽(1975),女,学士,副主任护师,主要从事泌尿系统肿瘤诊断与护理方面的研究
  • 基金资助:
    天津市教委项目;天津市应用基础及前沿技术研究计划重点项目

Progress in the detection of diagnostic markers for prostate cancer

LI Li, SONG Qian, LIU Ran-lu△   

  1. Department of Urology, the Second Hospital of Tianjin Medical University, Tianjin 300211, China
  • Received:2019-03-15 Revised:2019-04-18 Published:2019-08-15 Online:2019-08-16

摘要: 摘要:近年来,我国前列腺癌(PCa)的发病率呈显著增高的态势。同时,相较于发达国家,我国PCa患者的死亡 率较高。在过去10年中,用于PCa诊断的生物标志物的相关研究取得了较大进展,这些标志物检测证据基础也在迅 速发展。本文对PCa生物标志物检测领域的最新研究进展加以综述,以期为临床医务人员更好地进行决策提供 借鉴。

关键词: 前列腺肿瘤, 前列腺特异抗原, 生物标记, 肿瘤, 外泌体, 前列腺抗原3, 前列腺健康指数

Abstract: Abstract: In recent years, the incidence of prostate cancer in China has increased significantly. At thesame time,compared with developed countries, the mortality rate of prostate cancer in China is higher. In the past decade, the relevant research on biomarkers for the diagnosis of prostate cancer has made great progress, and the evidence base for the detection of these markers is also rapidly developing. We reviewed a large number of literatures and reviewed the latest developments in the field of prostate cancerbiomarker testing in order to provide a reference for clinical medical staff to make better decisions.

Key words: prostatic neoplasms, prostate-specific antigen, biomarkers, tumor, exosomes, prostate cancer antigen 3, prostate health index