Current research of the mechanism of estrogen on osteoclasts

doi:10.11958/20160070

Tianjin Med J ›› 2016, Vol. 44 ›› Issue (7): 925-928.doi: 10.11958/20160070

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Current research of the mechanism of estrogen on osteoclasts

SUN Xiaolei, ZHAO Zhihu, MA Xinlong

Tianjin Hospital, Tianjin 300211, China

Received:2016-02-23 Revised:2016-04-26 Published:2016-07-15 Online:2016-07-15
Contact: Xiao-Lei SUN E-mail:xlspine@163.com

SUN Xiaolei, ZHAO Zhihu, MA Xinlong. Current research of the mechanism of estrogen on osteoclasts[J]. Tianjin Med J, 2016, 44(7): 925-928.

Abstract

Abstract: Estrogen involved in the process of postmenopausal osteoporosis and the main functional cell is osteoclasts. However, the action mechanism of estrogen on the osteoclasts is unclear. Here we demonstrate the estrogen can affect the osteoclasts in three aspects: morphology and structure, apoptosis of osteoclasts and preosteoclasts to give an overall explanation for the estrogen to the osteoclasts.

Key words: Estrogen, Osteoclasts, Review, osteporosis

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Current research of the mechanism of estrogen on osteoclasts

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