Abstract: Objective To explore the implementation styles on the therapeutic effects on the neurosurgical intensive care unit (NICU) patients. Methods Patients were enrolled during February 3, 2015 to February 3, 2016. The key point time was August 3, 2015 when the treatment in our NICU was fully implemented by NICU professional doctors. Based on this time point, all the enrolled patients were divided into non-NICU professional doctor implementing (NNPDI) group and NICU professional doctor implementing (NPDI) group. Thus non- NICU professional doctors and professional doctors were the leaders of diagnosis and treatment in tow groups. The length of hospital stay, complications, prognosis and other therapeutic outcomes were compared between two groups. Results The length of hospital stay was longer in NPDI group than that in NNPDI group (P＜0.05). The incidence of water-electrolyte imbalance was lower in NPDI group than that in NNPDI group (P＜0.05). There were no significant differences in the incidence of the ventilator-associated pneumonia (VAP), the hepatic and renal insufficiency, the intracranial infections and stress ulcers between the two groups (P＞0.05). The proportion of referral to other wards and fatality rate were both lower in NPDI group than those in NNPDI group (P＜0.05). And the discharge rate from NICU was higher in NPDI group than that of NNPDI group (P＜0.05). There was no significant difference in the rate of patients left hospital without treatment between the two groups (P＞0.05). Conclusion The NICU professional doctor implementing may be contribute to, at least in part, the improving of prognosis of NICU patients without obvious advantages in most complications. The level of professional management remains to be improved.

Key words: water-electrolyte imbalance, prognosis, neurosurgical intensive care unit (NICU), treatment, case fatality rate