Abstract: Primary malignant melanoma of ovary is rare clinically, with high malignancy and poor prognosis. This article retrospectively analyzed a case of primary ovarian malignant melanoma with mature teratoma. The patient showed abdominal distension, and the pelvic magnetic resonance imaging showed a large cystic solid mass in the pelvic cavity, and a large amount of fluid in the pelvic and abdominal cavity. Surgical treatment was given. Histopathological result was confirmed as primary ovarian malignant melanoma with mature teratoma. The patient died of multiple orgon failure after 4 months of followed-up. This paper reviewed the relevant literature to improve the understanding of the disease.

Key words: ovarian neoplasms, melanoma, primary, diagnosis, differential, prognosis, therapy, teratoma