Effects of seasonal and temperature changes on blood glucose levels in patients with acute cerebral infarction

doi:10.11958/20212829

Abstract

Abstract:

Objective To investigate the effects of seasonal and temperature changes on blood glucose levels in patients with acute cerebral infarction. Methods The meteorological data of 1 260 cases with acute cerebral infarction were retrospectively analyzed. The baseline clinical data and blood test results were collected. The correlation between blood glucose levels in patients with acute cerebral infarction and seasonal and temperature changes were analyzed. Results The blood pressure, body mass index, baseline National Institutes of Health Stroke Scale score, total cholesterol and fasting plasma glucose (FPG) of patients with acute cerebral infarction were significantly higher in winter than those in summer (P<0.05). When the glycated hemoglobin A1c (HbA1c) level was ≥7%, the above indicators in spring were higher than those in other seasons (P<0.05). FPG levels peaked in January and bottomed in July, while HbA1c levels peaked in February and bottomed in August. Glucose levels showed a tendency to increase with the decrease of temperature. There was a lag effect of temperature on HbA1c. Spearman correlation test was performed on temperature and glucose levels. It was found that FPG levels were negatively correlated with monthly mean daily temperature, monthly minimum daily temperature and monthly maximum daily temperature (r_s=-0.690, -0.637, -0.764, respectively, all P<0.05). HbA1c levels were negatively correlated with monthly mean daily temperature, monthly minimum daily temperature and monthly maximum daily temperature with a two-month lag (r_s=-0.729, -0.750, -0.743, respectively, all P<0.05). Conclusion The blood glucose level of patients with acute cerebral infarction complicated with diabetes is higher in winter than that in other seasons. The monthly mean daily temperature, monthly minimum temperature and monthly maximum temperature are negatively correlated with blood glucose level.

Key words: brain infarction, acute disease, diabetes mellitus, blood glucose, hemoglobin A, glycosylated, seasons, climate, temperature

CLC Number:

R743.33

Figures/Tables 4

Tab.1 Comparison of general data of patients with acute cerebral infarction between different seasons

Tab.2 Comparison of blood metabolic index results between the four groups

Fig.1 The trends of fasting plasma glucose levels and temperature in different months

Fig.2 Changes of glycated hemoglobin A1c levels in different months and temperature with a two-month lag

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