Abstract: Abstract Objective: Using olfactory event related potential (OERP) and magnetic resonance imaging (MRI) to evaluate olfactory function. Methods: Eleven healthy individuals with normal olfactory function (NL) and 11 patients with nasal polyposis (NP), 11 with posttraumatic olfactory loss (PT), and 11 with postinfectious olfactory loss(PI) were included in this study.Physical examination,nasal endoscopy, T&T olfactory testing, olfactory event related potentials and magnetic resonance imaging were performed in all patients. Results: T&T olfactory testing revealed that NL individuals had higher scores than patients with NP,PT, or PI. OERP testing were recorded in the 11 NL individuals and in 3 NP, 3 PT, and 4 PI patients. The OB volumes were higher in NL individuals compared with NP, PT, and PI patients. The OB volumes in PT patients were significantly lower than those from NP and PI patients. Conclusion: This finding suggests that these diagnostic tools provide information in terms of the clinical assessment of olfactory function.

Key words: Olfaction disorders, Olfactory event-related potential, Magnetic resonance imaging, Olfactory bulb volume