Abstract: Objective: To discuss the relationship between the level of serum electrolytes(K+, Na+, Cl-) and severity of angiographic coronary artery disease. Methods: The study population consisted of 264 patients who underwent coronary angiography for suspected CAD was divided into two groups, the coronary artery disease (CAD) group and the non-CAD group. The CAD group was divided into acute myocardial infarction (AMI) subgroup and non-AMI subgroup. Then to compare the level of serum electrolytes(K+, Na+, Cl-) and other main measurements between two groups and two subgroups. Meanwhile to evaluate the correlation analysis result between all measurements and the number of diseased coronary arteries. Results: The serum potassium level of CAD group was higher than that in non-CAD group (P<0.05), on the contrary, the serum sodium and chlorine concentration of CAD group were both lower than those in another group(P<0.05 or P<0.01). The serum potassium level of AMI subgroup was higher than that in non-AMI subgroup (P<0.01), the serum chlorine concentration of AMI subgroup was lower than that in another subgroup (P<0.05).There was no statistical difference of serum sodium concentration between two subgroups. The correlation analysis indicated that serum potassium level positively correlated with the number of diseased coronary arteries (P<0.05), but sodium and chlorine levels negatively correlated with the number of diseased coronary arteries(P<0.01). Conclusion: Increasing of K+ level and decreasing of Na+ and Cl- levels had correlation with severity of angiographic coronary artery disease.

Key words: electrolytes, coronary angiography, correlation analysis, acute myocardial infarction, the number of diseased coronary arteries