• 综述 • Previous Articles     Next Articles

Current Research Progress of Apelin-13

FU wan 1,TIAN Shao wen2,YOU Yong 1   

  1. 1. Department of Neurology, First Affiliated Hospital, University of South China
    2. Department of Physiology, Medical School, University of South China
  • Received:2014-04-16 Revised:2014-06-11 Published:2014-11-15 Online:2014-11-15
  • Contact: FU wan

Abstract:

[Abstract] Apelin is a polypeptide consisting of 77 amino acids. Apelin receptors are found to be the angiotensinlike G protein coupled receptor (APJ). Apelin/APJ system is widely distributed in the peripheral and central nervous system.
Apelin-13 is one of the subtypes of Apelin, which has strong biological activity. This study reviewed the new research progress of Apelin-13 on physiological and pathological processes involved in the cardiovascular system, respiratory system, nervous system, digestive system and endocrine system.

Key words: Apelin-13, cardiovascular system, respiratory system, central nervous system, endocrine system