Abstract:

[Abstract] Objective   To evaluate the possible causes of misdiagnosis of minimal breast carcinoma (MBC). Methods   The possible causes of misdiagnosis of 90 cases of MBC confirmed by pathology were retrospective analyzed. Accord? ing to the maximum diameter of the lesion, 90 cases were divided into 0.5-1.0 cm group (n=55) and ≤0.5 cm group (n=35). And these two groups were subdivided into correct and misdiagnosed groups. The two-dimensional ultrasound findings were observed by using SIEMENZ S2000, GE vivid7 and GE vivid9 color Doppler ultrasound instruments, and reasons of misdiag? nosis were analyzed. Results  There were 32 cases were misdiagnosed in 90 patients with MBC. There was significant differ? ence in boundary of misdiagnosis between diameter 0.5-1.0 cm group and ≤0.5 cm group. There were significant differences in boundary and calcification between misdiagnosed group and correct group in diameter 0.5-1.0 cm group (P < 0.05). There were also significant differences in A/T ratio and accompanying by multiple benign nodules between misdiagnosed group and correct group in diameter ≤0.5 cm group (P < 0.05). Conclusion The misdiagnosis in MBC is because of different lesion sizes. The misdiagnosis happens in the maximum diameter of the lesions between 0.5-1.0 cm that showed manifestation of sharp edges, no micro-calcification in sonographic features of benign. The misdiagnosis happens in maximum diameter of le? sions ≤ 0.5 cm that manifested as the aspect A/T ratio <1 and characterized by multiple nodules

Key words: breast neoplasms, ultrasonography, doppler, color, diagnostic errors, minimal breast carcinoma