Abstract: Abstract: Objective To investigate the clinical characteristics and neonatal outcomes of 263 cases of uncomplicated twin pregnancy treated in the Affiliated Hospital of Yan'an University. Methods From January 2013 to December 2017, 263 cases of uncomplicated twin pregnancy were collected and divided into dichorionic diamniotic (DCDA) twin pregnancy group (n=206) and monochorionic diamniotic (MCDA) twin pregnancy group (n=57). The general data, pregnancy and perinatal complications and neonatal outcomes were compared between the two groups. Results In DCDA group, the natural conception rate was 69.9%, and the assisted reproductive conception rate was 30.1%, which was statistically significant compared with those of MCDA group (93.0% and 7.0%, P＜0.05). There were 123 cases with preterm delivery in DCDA group accounted for 59.7% (123/206), and 42 cases with preterm delivery (73.7%) in MCDA group. The incidence of neonatal adverse outcomes was 36.5% (148/405) in DCDA group, which was significantly lower than that of 49.1% (55/112) of MCDA group (P＜0.05). The incidence of neonatal asphyxia was significantly lower in DCDA group (10.1%, 41/405) than that in MCDA group (17.0%, 19/112, P＜0.05). Meanwhile, the conversion rate to neonatal intensive care unit (NICU) was significantly lower in the DCDA group (42.0%, 170/405) than that of MCDA group (53.6%, 60/112, P＜0.05). There were no significant differences in the incidence of neonatal respiratory distress syndrome (NRDS), pathological jaundice and infection between the two groups (P＞0.05). Conclusion For uncomplicated twin pregnancy cases, the standardized pregnancy management should be carried out according to DCDA or MCDA, and the timing of delivery should be individualized.

Key words: pregnancy, multiple, pregnancy complications, parturition, pregnancy outcome