Abstract: Abstract：Innate lymphocytes (ILCs) are a unique class of immune effector cells, which has been widely concerned in the past decade, especially the role of type 2 innate lymphocyte (ILC2) in allergic diseases and autoimmune diseases. ILC2 is involved in the formation of mucosal immunity, repairing and remodeling of tissue damage, and plays an important role in fighting infection, regulating inflammation and maintaining immune homeostasis. ILC2 is involved in the inflammatory response of allergic rhinitis, asthma, food allergy and eosinophil esophagitis, which cannot be ignored. This paper reviews the research progress of ILC2 in allergic diseases.

Key words: group 2 innate lymphoid cells, allergic disease, allergic rhinitis, asthma, atopic dermatitis